Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9005979 | 0.81 | KDM4E (0.36) | KDM4EHDAC6 | |
| SCHEMBL9005993 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1HDAC6 | |
| SCHEMBL8936196 | 0.68 | IGFBP5 (0.43) | KMT2A | |
| SCHEMBL9700784 | 0.64 | HDAC6 (0.41) | KDM4EALDH1A1HDAC6CHRM1 | |
| SCHEMBL9700703 | 0.64 | — | — | |
| SCHEMBL8708279 | 0.63 | TBXA2R (0.54) | KDM4EALDH1A1HDAC6 | |
| SCHEMBL8645093 | 0.63 | PRKAG1 (0.37) | — | |
| SCHEMBL8614149 | 0.63 | HDAC6 (0.70) | KDM4EALDH1A1KMT2AHDAC6 | |
| SCHEMBL3362000 | 0.63 | APP (0.46) | KDM4EALDH1A1KMT2AACHEBCHE | |
| SCHEMBL8644010 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736032-A1 | HETEROCYCLIC COMPOUNDS | Astra Aktiebolag (SE) | 1996-10-09 | — | — | EP | disclosed |
| WO-1995017410-A1 | HETEROCYCLIC COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1995-06-29 | — | — | WO | disclosed |