Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701633 | 0.84 | TAAR1 (0.57) | TAAR1 | |
| SCHEMBL9701935 | 0.83 | TAAR1 (0.52) | TAAR1ALDH1A1CYP1A2 | |
| SCHEMBL9701676 | 0.76 | KDM4E (0.56) | TAAR1CYP19A1ALDH1A1CYP1A2 | |
| SCHEMBL9702802 | 0.73 | ADRA1A (0.50) | TAAR1ALDH1A1 | |
| SCHEMBL9701904 | 0.73 | ADRA1A (0.58) | TAAR1 | |
| SCHEMBL9700914 | 0.71 | ALDH1A1 (0.41) | TAAR1ALDH1A1 | |
| SCHEMBL12107843 | 0.71 | ALDH1A1 (0.41) | TAAR1CYP19A1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL11113858 | 0.70 | CYP19A1 (0.40) | TAAR1CYP19A1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL1294588 | 0.69 | MAOB (0.40) | TAAR1CYP19A1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL1295084 | 0.69 | MAOB (0.40) | TAAR1CYP19A1ALDH1A1GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |