Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701935 | 0.79 | TAAR1 (0.52) | KDM4EALDH1A1HTTTSHRTAAR1 | |
| SCHEMBL9701633 | 0.77 | TAAR1 (0.57) | TAAR1AOC3 | |
| SCHEMBL9701904 | 0.76 | ADRA1A (0.58) | TAAR1KMT2AMEN1AOC3 | |
| SCHEMBL9700877 | 0.76 | TAAR1 (0.39) | ALDH1A1TAAR1CYP19A1CYP1A2 | |
| SCHEMBL9702070 | 0.74 | TAAR1 (0.40) | KDM4ECA2ALDH1A1LMNATSHR | |
| SCHEMBL13749955 | 0.74 | KDM4E (0.54) | KDM4EATMCA2ALDH1A1PPARG | |
| SCHEMBL9701928 | 0.73 | KDM4E (0.53) | KDM4ECA2ALDH1A1PPARGLMNA | |
| SCHEMBL9702162 | 0.73 | TAAR1 (0.54) | ALDH1A1LMNATSHRTAAR1KMT2A | |
| SCHEMBL1033641 | 0.73 | LMNA (0.61) | KDM4EATMCA2ALDH1A1LMNA | |
| SCHEMBL5730768 | 0.73 | CA2 (0.59) | KDM4EATMCA2ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |