Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 5/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702759 | 0.78 | MAPT (0.41) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL9702052 | 0.76 | ALDH1A1 (0.46) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL9701638 | 0.74 | EGFR (0.38) | EGFRCA12CA1CA2CA7 | |
| SCHEMBL9700915 | 0.72 | ALDH1A1 (0.38) | GAATDP1TAAR1ALDH1A1LMNA | |
| SCHEMBL9703351 | 0.72 | CA12 (0.42) | KDM4EGAACA12CA1CA2 | |
| SCHEMBL9702758 | 0.71 | HDAC1 (0.38) | KDM4EMAPTPOLBL3MBTL1RECQL | |
| SCHEMBL30434639 | 0.69 | KDM4E (0.45) | EGFRKDM4EMAPTGAACA12 | |
| SCHEMBL29473345 | 0.69 | CA12 (0.56) | KDM4EMAPTGAACA12CA1 | |
| SCHEMBL1703207 | 0.69 | CA12 (0.56) | KDM4EMAPTGAACA12CA1 | |
| Hydrochloric Acid SCHEMBL31534576 | 0.68 | ALPG (0.54) | KDM4EMAPTGAACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |