Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA7 | P43166 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702052 | 0.80 | ALDH1A1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9702759 | 0.78 | MAPT (0.41) | BACE1CA12CA1CA2CA7 | |
| SCHEMBL9700906 | 0.74 | EGFR (0.43) | EGFRCA12CA1CA2CA7 | |
| SCHEMBL9700914 | 0.72 | ALDH1A1 (0.41) | TAAR1 | |
| SCHEMBL9703351 | 0.68 | CA12 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9702172 | 0.68 | ALDH1A1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9700915 | 0.68 | ALDH1A1 (0.38) | TAAR1 | |
| SCHEMBL10442128 | 0.67 | ACHE (0.38) | BACE1ACHETAAR1 | |
| SCHEMBL9703287 | 0.64 | CA1 (0.46) | CA1CA2 | |
| SCHEMBL9701867 | 0.64 | CA2 (0.37) | EGFRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |