Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702172 | 0.85 | ALDH1A1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9702223 | 0.77 | KDM4E (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9702759 | 0.72 | MAPT (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9700906 | 0.72 | EGFR (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9700880 | 0.70 | ALDH1A1 (0.39) | CA1CA2ALOX5ALDH1A1KDM4E | |
| SCHEMBL9702052 | 0.70 | ALDH1A1 (0.46) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9701638 | 0.68 | EGFR (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11114038 | 0.68 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9700887 | 0.68 | EGFR (0.39) | TYR | |
| SCHEMBL9701867 | 0.67 | CA2 (0.37) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |