Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | RYR1 | P21817 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinoline SCHEMBL27720870 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTAKR1B1CYP11B1CYP11B2 | |
| SCHEMBL3899701 | 0.81 | CTSL (0.49) | ALDH1A1MAPTCTSLCYP11B1CYP11B2 | |
| SCHEMBL12920004 | 0.80 | ALDH1A1 (0.46) | ALDH1A1MAPTPARP10PARP11CTSL | |
| SCHEMBL1119381 | 0.78 | CYP11B1 (0.54) | ALDH1A1MAPTAKR1B1ERN1CYP11B1 | |
| SCHEMBL28094727 | 0.76 | MAPT (0.37) | ALDH1A1MAPTAKR1B1PARP1GPR35 | |
| SCHEMBL30288495 | 0.75 | CA2 (0.51) | ALDH1A1MAPTPNMTADRA2A | |
| SCHEMBL23473137 | 0.75 | AKR1B1 (0.43) | ALDH1A1MAPTAKR1B1ERN1S100A4 | |
| SCHEMBL7344244 | 0.74 | AKR1B1 (0.38) | ALDH1A1MAPTAKR1B1ERN1HTR2A | |
| SCHEMBL3920383 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTPARP10PARP11CTSL | |
| SCHEMBL17042492 | 0.73 | MAPT (0.41) | ALDH1A1MAPTAKR1B1ERN1S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | L'OREAL (FR) | 2004-11-25 | — | — | US | claimed |
| US-4013404-A | Method of dyeing hair with indolines, indoles and indazoles | AMERICAN CYANAMID COMPANY (US) | 1977-03-22 | — | — | US | claimed |
| EP-4613752-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2025-09-10 | — | — | EP | disclosed |
| US-20250270224-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | Xuanzhu Biopharmaceutical Co., Ltd. (CN) | 2025-08-28 | — | — | US | disclosed |
| CN-120092010-A | Polycyclic poly (ADP-ribose) polymerase selective inhibitors | 轩竹生物科技股份有限公司 | 2025-06-03 | — | — | CN | disclosed |
| CN-114829368-B | Method for sequencing by synthesis using a continuous labelling scheme | 豪夫迈·罗氏有限公司 | 2024-06-04 | — | — | CN | disclosed |
| WO-2024093956-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | 山东轩竹医药科技有限公司 | 2024-05-10 | — | — | WO | disclosed |
| EP-3898643-B1 | 3' REVERSIBLY PROTECTED NUCLEOTIDES FOR SEQUENCING BY SYNTHESIS USING NANOPORES | ROCHE DIAGNOSTICS GMBH (DE) | 2024-04-17 | — | — | EP | disclosed |
| US-20240058753-A1 | ELECTROPHORETIC DEVICES AND METHODS FOR NEXT-GENERATION SEQUENCING LIBRARY PREPARATION | ROCHE SEQUENCING SOLUTIONS INC (US) | 2024-02-22 | — | — | US | disclosed |
| US-20240010668-A1 | 3' PROTECTED NUCLEOTIDES | ROCHE SEQUENCING SOLUTIONS INC (US) | 2024-01-11 | — | — | US | disclosed |
| US-11773130-B2 | 3′ protected nucleotides | Roche Sequencing Solutions, Inc. (US) | 2023-10-03 | — | — | US | disclosed |
| US-5445934-A | Selective photoremovable groups on surface | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-08-29 | — | — | US | disclosed |
| US-5424186-A | Biosynthesis of oligonucleotides on solid substrate by irradiation of predefined segments to remove blocking agents; then coupling with nucleotide | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-06-13 | — | — | US | disclosed |
| US-5405783-A | Removing photoremovable protective group from region of substrate, contacting with protected amino acid, repeating to form peptide | AFFYMAX TECHNOLOGIES N.V. (AN) | 1995-04-11 | — | — | US | disclosed |
| EP-0619321-A1 | Very large scale immobilized peptide synthesis | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-10-12 | — | — | EP | disclosed |
| EP-0476014-B1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS | AFFYMAX TECH NV (AN) | 1994-08-31 | — | — | EP | disclosed |
| US-5143854-A | LARGE SCALE PHOTOLITHOGRAPHIC SOLID PHASE SYNTHESIS OF POLYPEPTIDES AND RECEPTOR BINDING SCREENING THEREOF | AFFYMAX TECHNOLOGIES N.V. (AN) | 1992-09-01 | — | — | US | disclosed |
| EP-0476014-A1 | VERY LARGE SCALE IMMOBILIZED POLYMER SYNTHESIS. | AFFYMAX TECH NV (NL) | 1992-03-25 | — | — | EP | disclosed |
| WO-1990015070-A1 | VERY LARGE SCALE IMMOBILIZED PEPTIDE SYNTHESIS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1990-12-13 | — | — | WO | disclosed |
| US-4013404-A | Method of dyeing hair with indolines, indoles and indazoles | AMERICAN CYANAMID COMPANY (US) | 1977-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240010668-A1 | 3' PROTECTED NUCLEOTIDES | NT5C3B, NSUN3, NSUN2 | ALDH1A1 4057/4885MAPT 4464/4885AKR1B1 4174/4885 |
| US-20250270224-A1 | POLYCYCLIC POLY(ADP-RIBOSE) POLYMERASE SELECTIVE INHIBITOR | PARP1, PARP11, PARP2 | ALDH1A1 1101/4885MAPT 2036/4885AKR1B1 967/4885 |
| US-11773130-B2 | 3′ protected nucleotides | NT5C3B, NSUN3, NSUN2 | ALDH1A1 4016/4885MAPT 4512/4885AKR1B1 4138/4885 |
| US-20040231067-A1 | Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses | KRT18, CDC73, PYCR1 | ALDH1A1 1097/4885MAPT 1406/4885AKR1B1 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.