Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703381 | 0.88 | LMNA (0.40) | GAATSHRLMNAMAPTKDM4E | |
| SCHEMBL9689269 | 0.82 | GAA (0.45) | GAATSHRLMNAMAPTHTT | |
| SCHEMBL9689527 | 0.81 | L3MBTL1 (0.48) | GAATSHRLMNAMAPTHTT | |
| SCHEMBL9689427 | 0.75 | CASP1 (0.65) | GAATSHRLMNAMAPTHTT | |
| SCHEMBL9227255 | 0.69 | HRH3 (0.33) | HTTALDH1A1CYP1A2CASP1CYP3A4 | |
| SCHEMBL9688189 | 0.69 | LMNA (0.40) | GAATSHRLMNAMAPTKDM4E | |
| SCHEMBL9073389 | 0.68 | HTR3E (0.44) | HTTTDP1KDM4EMAPK1ALDH1A1 | |
| SCHEMBL9689577 | 0.68 | LMNA (0.43) | GAATSHRLMNAMAPTTDP1 | |
| SCHEMBL29942613 | 0.67 | GAA (0.57) | GAATSHRLMNAMAPTHTT | |
| SCHEMBL24673156 | 0.67 | GAA (0.56) | GAATSHRLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |