Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701522 | 0.88 | GAA (0.45) | LMNATSHRALDH1A1KDM4EERCC1 | |
| SCHEMBL9688189 | 0.80 | LMNA (0.40) | LMNAHPGDALOX15TSHRALDH1A1 | |
| SCHEMBL9689577 | 0.79 | LMNA (0.43) | LMNAHPGDALOX15TSHRALDH1A1 | |
| SCHEMBL9227255 | 0.72 | HRH3 (0.33) | ALDH1A1HRH3 | |
| SCHEMBL9689529 | 0.71 | CASP1 (0.59) | LMNAHPGDALOX15TSHRSMN1; SMN2 | |
| SCHEMBL9073389 | 0.71 | HTR3E (0.44) | HPGDALDH1A1KDM4EMAPK1HRH3 | |
| SCHEMBL9689269 | 0.69 | GAA (0.45) | LMNAHPGDALOX15TSHRALDH1A1 | |
| SCHEMBL9689527 | 0.67 | L3MBTL1 (0.48) | LMNAHPGDALOX15TSHRALDH1A1 | |
| SCHEMBL1550059 | 0.65 | ALDH1A1 (0.50) | LMNAHPGDALOX15ALDH1A1KDM4E | |
| SCHEMBL9704351 | 0.64 | LMNA (0.40) | LMNAHPGDALOX15TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120843-A | Nervous system disorders | UPJOHN (US) | 1992-06-09 | — | — | US | disclosed |