Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700293 | 0.77 | ALDH1A1 (0.37) | GBA1ADH1BADH1CADH1AADH7 | |
| SCHEMBL29077882 | 0.66 | NOS1 (0.41) | GBA1NOS1NOS2 | |
| SCHEMBL7565494 | 0.64 | GBA1 (0.45) | GBA1 | |
| SCHEMBL8651297 | 0.63 | GBA1 (0.37) | GBA1 | |
| SCHEMBL8651985 | 0.63 | GBA1 (0.40) | GBA1ADH1BADH1CADH1AADH7 | |
| SCHEMBL29402028 | 0.62 | MEN1 (0.35) | NOS1NOS2 | |
| SCHEMBL6519938 | 0.62 | GBA1 (0.43) | GBA1 | |
| SCHEMBL9700271 | 0.62 | MMP3 (0.42) | — | |
| SCHEMBL10586325 | 0.62 | GBA1 (0.37) | GBA1 | |
| SCHEMBL21538649 | 0.62 | HPGD (0.50) | SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120884-A | Preparation of hydroxy arylcyclobutenes | THE DOW CHEMICAL COMPANY (US) | 1992-06-09 | — | — | US | disclosed |