Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GLA | P06280 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701530 | 0.83 | KDM4E (0.65) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9526844 | 0.82 | KDM4E (0.55) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701620 | 0.82 | KDM4E (0.57) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701293 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701665 | 0.80 | KDM4E (0.61) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701460 | 0.78 | ALDH1A1 (0.52) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9701927 | 0.78 | KDM4E (0.55) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7371751 | 0.77 | KDM4E (0.57) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL7371748 | 0.77 | KDM4E (0.57) | ALDH1A1KDM4EGLAGAAL3MBTL1 | |
| SCHEMBL9526258 | 0.77 | KDM4E (0.64) | ALDH1A1KDM4EGLAGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |