Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC2 | O75106 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701919 | 0.81 | MEN1 (0.43) | NPSR1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9700908 | 0.78 | HTR1B (0.57) | NPSR1MAPTMEN1LMNAKMT2A | |
| SCHEMBL9702039 | 0.76 | SMN1; SMN2 (0.47) | MAPTMEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL9702021 | 0.76 | MAOB (0.50) | AOC2MAOAMAOBALOX15MEN1 | |
| SCHEMBL5786743 | 0.72 | NOTUM (0.51) | AOC2MAOAMAOBNOTUMNPSR1 | |
| Ethylene SCHEMBL27514111 | 0.71 | ALOX15 (0.51) | AOC2MAOAMAOBALOX15NOTUM | |
| SCHEMBL3528979 | 0.71 | KDM4E (0.68) | AOC2MAOAMAOBALOX15MAPT | |
| SCHEMBL3238659 | 0.70 | ALOX15 (0.55) | AOC2MAOAMAOBALOX15NOTUM | |
| SCHEMBL1395765 | 0.70 | HTT (0.61) | AOC2MAOAMAOBNOTUMNPSR1 | |
| SCHEMBL27383228 | 0.70 | SMN1; SMN2 (0.59) | NOTUMNPSR1MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |