Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702788 | 0.79 | TAAR1 (0.42) | TSHRMAPK1ALDH1A1POLBTAAR1 | |
| SCHEMBL9702070 | 0.78 | TAAR1 (0.40) | SMN1; SMN2TSHRMAPK1ALDH1A1TAAR1 | |
| SCHEMBL9701657 | 0.76 | AOC2 (0.55) | SMN1; SMN2TSHRALDH1A1LMNAMAPT | |
| SCHEMBL9702814 | 0.76 | LMNA (0.39) | SMN1; SMN2MAPK1ALDH1A1TAAR1GAA | |
| SCHEMBL9703429 | 0.76 | MAOB (0.49) | L3MBTL1TAAR1GAALMNAMAPT | |
| SCHEMBL9700886 | 0.75 | CA12 (0.47) | SMN1; SMN2TSHRALDH1A1TAAR1GAA | |
| SCHEMBL9701919 | 0.73 | MEN1 (0.43) | SMN1; SMN2L3MBTL1TSHRPOLBMAPT | |
| SCHEMBL9702162 | 0.73 | TAAR1 (0.54) | SMN1; SMN2TSHRALDH1A1TAAR1GAA | |
| SCHEMBL7407020 | 0.72 | SMN1; SMN2 (0.73) | SMN1; SMN2L3MBTL1TSHRMAPK1ALDH1A1 | |
| SCHEMBL9701958 | 0.72 | KMT2A (0.44) | SMN1; SMN2L3MBTL1ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |