Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701657 | 0.81 | AOC2 (0.55) | MEN1KMT2ASMN1; SMN2MAPTTSHR | |
| SCHEMBL9700908 | 0.78 | HTR1B (0.57) | MEN1KMT2ASMN1; SMN2TDP1MAPT | |
| SCHEMBL9702021 | 0.76 | MAOB (0.50) | MEN1KMT2A | |
| SCHEMBL9702766 | 0.73 | MAOB (0.44) | POLBRAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL9702039 | 0.73 | SMN1; SMN2 (0.47) | MEN1KMT2APOLBSMN1; SMN2MAPT | |
| SCHEMBL1032880 | 0.71 | KDM4E (0.68) | MEN1KMT2ARAB9ASMN1; SMN2TDP1 | |
| SCHEMBL3505391 | 0.71 | AOC2 (0.68) | MEN1KMT2APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL5570337 | 0.70 | L3MBTL1 (0.48) | MEN1KMT2ARAB9ASMN1; SMN2TDP1 | |
| SCHEMBL4093120 | 0.70 | WDR5 (0.50) | MEN1KMT2APOLBRAB9ASMN1; SMN2 | |
| SCHEMBL1032879 | 0.70 | KDM4E (0.61) | MEN1KMT2APOLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |