Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | F7 | P08709 | 2/20 | 0.43 |
| ▸ | F3 | P13726 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700475 | 0.77 | FAAH (0.52) | FAAHCES1 | |
| Hydrochloric Acid SCHEMBL19691934 | 0.71 | FAAH (0.53) | SOAT1FAAHCES1 | |
| Hydrochloric Acid SCHEMBL4199343 | 0.70 | FAAH (0.52) | KDM4ESOAT1FAAHCES1ALDH1A1 | |
| SCHEMBL13662384 | 0.66 | FAAH (0.62) | FAAHCES1 | |
| Hydrochloric Acid SCHEMBL10938083 | 0.66 | TERT (0.61) | SOAT1FAAHCYP3A4MEN1TP53 | |
| Oleamide SCHEMBL15533923 | 0.66 | FAAH (0.85) | KDM4ESOAT1FAAHCYP3A4MEN1 | |
| Oleamide SCHEMBL2906344 | 0.66 | FAAH (0.85) | KDM4ESOAT1FAAHCYP3A4MEN1 | |
| Oleamide SCHEMBL6366127 | 0.66 | FAAH (0.85) | KDM4ESOAT1FAAHCYP3A4MEN1 | |
| Oleamide SCHEMBL6366123 | 0.66 | FAAH (0.85) | KDM4ESOAT1FAAHCYP3A4MEN1 | |
| Oleamide SCHEMBL15533927 | 0.66 | FAAH (0.85) | KDM4ESOAT1FAAHCYP3A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0518458-A1 | Fatty imidazolium salts | TEXACO CHEMICAL COMPANY (US) | 1992-12-16 | — | — | EP | disclosed |