Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701958 | 0.85 | KMT2A (0.44) | CTSDHPGDNPC1HTTTP53 | |
| SCHEMBL9703267 | 0.81 | CA12 (0.44) | HPGDTAAR1CA1CA2CA12 | |
| SCHEMBL9701621 | 0.79 | ALDH1A1 (0.57) | HPGDNPC1TAAR1HTTCA1 | |
| SCHEMBL9701879 | 0.79 | MAPT (0.47) | HPGDTAAR1HTTCA1CA2 | |
| SCHEMBL9702223 | 0.74 | KDM4E (0.42) | HPGDNPC1TAAR1CA1CA2 | |
| SCHEMBL16891415 | 0.74 | ALDH1A1 (0.39) | HPGDNPC1CA1CA2CA12 | |
| SCHEMBL2199445 | 0.73 | CTSD (0.62) | CTSDHPGDNPC1HTTTP53 | |
| Hydrochloric Acid SCHEMBL1533315 | 0.71 | CTSD (0.61) | CTSDHPGDNPC1HTTTP53 | |
| Hydrochloric Acid SCHEMBL30301353 | 0.71 | CTSD (0.61) | CTSDHPGDNPC1HTTTP53 | |
| SCHEMBL9701949 | 0.71 | MAOB (0.54) | HPGDCA1CA2CA12CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |