Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702182 | 0.73 | — | — | |
| SCHEMBL9702021 | 0.73 | MAOB (0.50) | TAAR1 | |
| SCHEMBL707494 | 0.72 | KDM4E (0.44) | — | |
| SCHEMBL3504982 | 0.71 | MAOB (0.57) | — | |
| SCHEMBL18906071 | 0.68 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL341114 | 0.68 | ALOX15 (0.50) | — | |
| SCHEMBL9701657 | 0.68 | AOC2 (0.55) | — | |
| SCHEMBL9701919 | 0.68 | MEN1 (0.43) | — | |
| SCHEMBL11008232 | 0.67 | KMT2A (0.39) | — | |
| SCHEMBL724289 | 0.67 | GSK3B (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |