Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 6/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700887 | 0.86 | EGFR (0.39) | TYR | |
| SCHEMBL9701903 | 0.79 | TAAR1 (0.52) | TSHR | |
| SCHEMBL9702029 | 0.74 | TAAR1 (0.48) | KMT2ATDP1 | |
| SCHEMBL9701625 | 0.72 | DRD2 (0.55) | KMT2AMAPTCYP3A4ALOX15 | |
| SCHEMBL9703273 | 0.72 | LMNA (0.37) | TYRMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL632515 | 0.71 | TYR (0.74) | TYRALOX5MEN1KMT2AMAPT | |
| SCHEMBL29465001 | 0.71 | TYR (0.74) | TYRALOX5MEN1KMT2AMAPT | |
| SCHEMBL633312 | 0.71 | TYR (0.65) | TYRALOX5MEN1KMT2AMAPT | |
| SCHEMBL30255614 | 0.71 | TYR (0.65) | TYRALOX5MEN1KMT2AMAPT | |
| SCHEMBL10442128 | 0.71 | ACHE (0.38) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |