Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ABAT | P80404 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701924 | 0.82 | LOXL2 (0.43) | TAAR1 | |
| SCHEMBL10442128 | 0.80 | ACHE (0.38) | TAAR1BACE1 | |
| Hydrochloric Acid SCHEMBL11493475 | 0.80 | LOXL2 (0.41) | TAAR1 | |
| SCHEMBL9701928 | 0.79 | KDM4E (0.53) | TAAR1SLC6A2KDM4EALDH1A1HTR1A | |
| SCHEMBL9701935 | 0.78 | TAAR1 (0.52) | TAAR1KDM4EALDH1A1CYP2C19 | |
| SCHEMBL9701625 | 0.78 | DRD2 (0.55) | TAAR1KDM4EBLMKMT2A | |
| SCHEMBL9700887 | 0.74 | EGFR (0.39) | BACE1 | |
| SCHEMBL9701922 | 0.72 | ESR1 (0.41) | SLC6A2CYP2C19ESR1ESR2 | |
| SCHEMBL9701676 | 0.71 | KDM4E (0.56) | TAAR1KDM4EALDH1A1KMT2ACA2 | |
| SCHEMBL9701911 | 0.71 | TAAR1 (0.35) | TAAR1KDM4EALDH1A1TDP1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |