Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 2/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10442128 | 0.82 | ACHE (0.38) | DRD2DRD1TAAR1ENPP2CYP3A4 | |
| SCHEMBL9701924 | 0.80 | LOXL2 (0.43) | TAAR1 | |
| Hydrochloric Acid SCHEMBL11493475 | 0.78 | LOXL2 (0.41) | TAAR1 | |
| SCHEMBL9702029 | 0.78 | TAAR1 (0.48) | TAAR1KMT2AKDM4EBLM | |
| SCHEMBL9701928 | 0.77 | KDM4E (0.53) | DRD2DRD1TAAR1CYP1A2CYP3A4 | |
| SCHEMBL9701911 | 0.73 | TAAR1 (0.35) | TAAR1ALOX15KDM4ELMNAMAPT | |
| SCHEMBL9702218 | 0.72 | APP (0.43) | DRD2DRD1TAAR1ENPP2MAPK1 | |
| SCHEMBL43719 | 0.71 | TAAR1 (1.00) | DRD2DRD1TAAR1ENPP2CYP1A2 | |
| SCHEMBL29465557 | 0.71 | TAAR1 (1.00) | DRD2DRD1TAAR1ENPP2CYP1A2 | |
| SCHEMBL29598265 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |