Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ARHGEF12 | Q9NZN5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9700809 | 0.72 | — | — | |
| SCHEMBL9701943 | 0.70 | KDM4E (0.38) | KMT2AKDM4EL3MBTL1 | |
| SCHEMBL29039963 | 0.69 | NLRP3 (0.41) | ALDH1A1KMT2A | |
| SCHEMBL6495560 | 0.69 | LOXL2 (0.47) | ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6495555 | 0.68 | LOXL2 (0.46) | ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL6495563 | 0.68 | LOXL2 (0.46) | ALDH1A1MAPTKDM4E | |
| SCHEMBL25919492 | 0.65 | ALDH1A1 (0.39) | ALDH1A1KMT2A | |
| SCHEMBL28572795 | 0.65 | PTGS2 (0.35) | ALDH1A1GRIN3BGRIN1GRIN2CMEN1 | |
| SCHEMBL29671111 | 0.65 | PTGS2 (0.35) | ALDH1A1GRIN3BGRIN1GRIN2CMEN1 | |
| SCHEMBL7421530 | 0.65 | SMN1; SMN2 (0.33) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992014740-A1 | QUINOXALINE PHOSPHONO-AMINO ACIDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-03 | — | — | WO | disclosed |
| US-5118675-A | Therapy for central nervous system disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-02 | — | — | US | disclosed |