Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | CCR4 | P51679 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28283268 | 0.80 | CA1 (0.38) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL7761256 | 0.79 | ALDH1A1 (0.44) | CA1CA2TRPV4SLC22A12ALDH1A1 | |
| SCHEMBL2570257 | 0.79 | SLC22A12 (0.47) | TRPV4SLC22A12ALDH1A1CCR4MAPT | |
| SCHEMBL970204 | 0.78 | TRPV4 (0.42) | TRPV4EPAS1SLC22A12ALDH1A1HTT | |
| SCHEMBL4972108 | 0.78 | CYP1A2 (0.43) | TRPV4EPAS1SLC22A12ALDH1A1HTT | |
| SCHEMBL4021727 | 0.77 | ALDH1A1 (0.56) | CA1CA2CA4CA6PLCG1 | |
| SCHEMBL1343169 | 0.75 | DYRK1A (0.42) | CXCR1CXCR2ALDH1A1DYRK1ATLR8 | |
| SCHEMBL841244 | 0.74 | CA2 (0.46) | CA1CA2CA4CA6TRPV4 | |
| SCHEMBL3247679 | 0.74 | NPC1 (0.49) | TRPV4EPAS1SLC22A12ALDH1A1CCR4 | |
| SCHEMBL8071 | 0.73 | CA1 (0.62) | CA1CA2CA4CA6PLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563057-A | Sulfonamide compounds or its salt | 大鹏药品工业株式会社 | 2019-04-02 | — | — | CN | disclosed |
| WO-2009087085-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-07-16 | — | — | WO | disclosed |