⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18132867 | 0.93 | USP2 (0.39) | — | |
| SCHEMBL14884816 | 0.84 | — | — | |
| SCHEMBL247326 | 0.84 | — | — | |
| SCHEMBL252175 | 0.84 | INMT (0.39) | — | |
| Oxalic Acid SCHEMBL18118015 | 0.82 | HPGD (0.43) | — | |
| SCHEMBL21124042 | 0.76 | NOS3 (0.30) | — | |
| SCHEMBL22060208 | 0.73 | LMNA (0.34) | — | |
| SCHEMBL6600764 | 0.71 | NOS3 (0.33) | — | |
| SCHEMBL18155275 | 0.71 | NOS3 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7818495 | 0.70 | NOS3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019111020-A1 | ß-LACTONE COMPOUNDS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-06-13 | — | — | WO | disclosed |
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| JP-2002003490-A | METHOD FOR PRODUCING 1-(THIAZOLIN-2-YL)AZETIDINE DERIVATIVE | WYETH LEDERLE JAPAN LTD | 2002-01-09 | — | — | JP | disclosed |
| US-5856475-A | 4-thia-1-azabicyclo/3.2.0/Heptane-3-Imino-2-isopropylidene-7-oxo-analogons of beta-lactams, processes for their preparation and the use thereof | PLIVE, FARMACEUTSKA, KEMIJSKA, PREHRAMBENA I KOZMETICKA INDUSTRIJA, DIONICKO DRUSTVO (HR) | 1999-01-05 | — | — | US | disclosed |
| CN-1171403-A | 4 -thia -1 -azabicyclo [3. 2. 0] heptane -3 -imino -2 -isopropylidene -7 -oxo analogons of beta -lactams, processes for their preparation and use thereof | PLIVA PHARM & CHEM WORKS (HR) | 1998-01-28 | — | — | CN | disclosed |
| EP-0796857-A1 | 4-thia-1-azabicyclo(3.2.0)heptane-3-imino-2-isopropylidene-7-oxo analogons of beta-lactams, processes for their preparation and the use thereof | PLIVA farmaceutska, kemijska, prehrambena i kozmeticka industrija, dionicko drustvo (HR) | 1997-09-24 | — | — | EP | disclosed |