Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.66 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703418 | 0.96 | OPRM1 (0.66) | OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL9767788 | 0.91 | OPRM1 (0.66) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9494728 | 0.87 | SIGMAR1 (0.67) | OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL9702348 | 0.83 | SIGMAR1 (0.67) | OPRM1OPRK1OPRD1SIGMAR1 | |
| SCHEMBL9493356 | 0.81 | OPRM1 (0.69) | OPRM1OPRK1 | |
| SCHEMBL8761982 | 0.81 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL5674183 | 0.81 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL4545380 | 0.81 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL10589759 | 0.80 | SIGMAR1 (0.76) | OPRM1OPRK1OPRD1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3078695 | 0.80 | OPRM1 (1.00) | OPRM1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130329-A | Amino, amide substituted compounds | ROUSSEL UCLAF (FR) | 1992-07-14 | — | — | US | disclosed |
| US-5068244-A | Benzcarbocyclic amides with nitro groups | ROUSSEL UCLAF (FR) | 1991-11-26 | — | — | US | disclosed |