Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.66 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.66 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703418 | 0.91 | OPRM1 (0.66) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9702542 | 0.91 | OPRM1 (0.66) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9767727 | 0.86 | SIGMAR1 (0.66) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9767758 | 0.85 | SIGMAR1 (0.65) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9767787 | 0.82 | OPRM1 (0.67) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL5674183 | 0.80 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL4545380 | 0.80 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL8761982 | 0.80 | OPRM1 (0.98) | OPRM1OPRK1SIGMAR1 | |
| SCHEMBL9772298 | 0.80 | SIGMAR1 (0.50) | OPRM1OPRK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3078695 | 0.79 | OPRM1 (1.00) | OPRM1OPRK1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272982-B1 | INDANE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES OBTAINED, THEIR USE AS MEDICINES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1991-04-17 | — | — | EP | claimed |
| US-4988727-A | Cardiovascular disorders, analgesics | ROUSSEL UCLAF (FR) | 1991-01-29 | — | — | US | disclosed |
| US-4888355-A | Indanes and their use as antiarrhythmic agents | ROUSSEL UCLAF (FR) | 1989-12-19 | — | — | US | disclosed |