Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL950001 | 0.83 | CYP3A4 (0.60) | CYP3A4CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL9700701 | 0.79 | NOTUM (0.41) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9528770 | 0.77 | KDM4E (0.48) | CYP3A4TP53USP2RAB9ANPC1 | |
| SCHEMBL9700756 | 0.76 | SNCA (0.37) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9701671 | 0.76 | BRD4 (0.42) | ALDH1A1KDM4ELMNAGAAHPGD | |
| SCHEMBL9526113 | 0.75 | MAPT (0.41) | CYP3A4CYP2D6CYP2C19MEN1KMT2A | |
| SCHEMBL9700666 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL9700407 | 0.75 | IDO1 (0.41) | KMT2AUSP2RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9701382 | 0.74 | SMN1; SMN2 (0.42) | CYP2D6CYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL9701656 | 0.74 | GAA (0.55) | CYP3A4CYP2D6CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | claimed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |