Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11336367 | 0.82 | L3MBTL1 (0.58) | KMT2APTGESALOX5PPARGMAPT | |
| SCHEMBL11322929 | 0.81 | KMT2A (0.55) | PTPN11KMT2ALMNAL3MBTL1 | |
| SCHEMBL20496450 | 0.79 | LMNA (0.52) | PTPN11KMT2APPARGMAPTSMN1; SMN2 | |
| SCHEMBL28567793 | 0.79 | L3MBTL1 (0.62) | KMT2ANPC1MAPTNFKB1RAB9A | |
| SCHEMBL11555374 | 0.78 | MAOB (0.57) | PTPN11KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL23504466 | 0.78 | ABCB1 (0.50) | ABCB1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL2648115 | 0.77 | SMN1; SMN2 (0.46) | NPC1NFKB1RAB9ANFKB2RELA | |
| SCHEMBL17637149 | 0.77 | HSD11B1 (0.63) | KMT2ANPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7303774 | 0.77 | KMT2A (0.46) | PTPN11KMT2AMAPTLMNAL3MBTL1 | |
| SCHEMBL11330584 | 0.76 | L3MBTL1 (0.65) | PTPN11KMT2APTGESALOX5PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |