Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322929 | 0.85 | KMT2A (0.55) | KMT2AL3MBTL1LMNAHTTPTPN11 | |
| SCHEMBL4729840 | 0.83 | KDM4E (0.57) | L3MBTL1MAPTHSD17B10LMNAHTT | |
| SCHEMBL6487232 | 0.83 | HPGD (0.52) | MAPTHSD17B10LMNACA9PTPN11 | |
| SCHEMBL11328546 | 0.83 | PLA2G2A (0.48) | KMT2AL3MBTL1PLK1MAPTHSD17B10 | |
| SCHEMBL13332125 | 0.82 | THRA (0.50) | KMT2AL3MBTL1MAPTPTPN11 | |
| SCHEMBL11331647 | 0.81 | L3MBTL1 (0.48) | KMT2AL3MBTL1MAPTHSD17B10LMNA | |
| SCHEMBL7164453 | 0.81 | HDAC1 (0.55) | L3MBTL1MAPTHSD17B10HTTCA9 | |
| SCHEMBL20496450 | 0.80 | LMNA (0.52) | KMT2AL3MBTL1PNLIPMAPTLMNA | |
| SCHEMBL9402736 | 0.79 | PTPN11 (0.54) | KMT2AMAPTLMNAPTPN11 | |
| SCHEMBL11364359 | 0.79 | ALDH1A1 (0.55) | KMT2AL3MBTL1MAPTLMNAPTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636626-A1 | Pyrazolopyrimidine Derivatives | LABORATOIRES GLAXO SA (FR) | 1995-02-01 | — | — | EP | disclosed |
| US-4276430-A | FOR TOPICAL APPLICATION AND SYSTEMIC ADMINISTRATION; ESTERS OF DIHYDROXYBENZOIC ACID | THE PROCTER & GAMBLE COMPANY (US) | 1981-06-30 | — | — | US | disclosed |