Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702162 | 0.86 | TAAR1 (0.54) | TAAR1ALDH1A1MEN1KMT2AGAA | |
| SCHEMBL9702070 | 0.81 | TAAR1 (0.40) | TAAR1CA12CA1CA2CA14 | |
| SCHEMBL9702039 | 0.79 | SMN1; SMN2 (0.47) | TAAR1ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL11113169 | 0.75 | CA12 (0.43) | TAAR1CA12CA1CA2CA14 | |
| SCHEMBL30839502 | 0.74 | TAAR1 (0.69) | TAAR1CA12CA1CA2CA14 | |
| SCHEMBL151944 | 0.74 | TAAR1 (0.69) | TAAR1CA12CA1CA2CA14 | |
| SCHEMBL9702802 | 0.73 | ADRA1A (0.50) | TAAR1CA12CA1CA2CA14 | |
| SCHEMBL9701904 | 0.73 | ADRA1A (0.58) | TAAR1MEN1KMT2A | |
| SCHEMBL622628 | 0.73 | CA12 (0.53) | TAAR1CA12CA1CA2CA14 | |
| SCHEMBL1032325 | 0.73 | CA12 (0.50) | CA12CA1CA2CA14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |