Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 10/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9019069 | 0.73 | ALDH1A1 (0.46) | KDM4EALDH1A1KMT2AHPGDGAA | |
| SCHEMBL9703660 | 0.72 | AR (0.51) | KDM4EALDH1A1KMT2AHPGDGAA | |
| SCHEMBL9019130 | 0.68 | USP2 (0.38) | KDM4EALDH1A1KMT2AHPGDGAA | |
| SCHEMBL9019009 | 0.67 | MAOB (0.45) | KDM4EALDH1A1KMT2AHPGDGAA | |
| SCHEMBL9019106 | 0.66 | MAOB (0.41) | KDM4EALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL18188062 | 0.63 | ALDH1A1 (0.56) | KDM4EALDH1A1KMT2AHPGDGAA | |
| SCHEMBL9019083 | 0.62 | KDM4E (0.43) | KDM4EALDH1A1KMT2AHPGDGAA | |
| SCHEMBL9019128 | 0.61 | KDM4E (0.42) | KDM4EALDH1A1KMT2AHPGDGAA | |
| SCHEMBL3173849 | 0.60 | AR (0.69) | ARPGR | |
| SCHEMBL4446050 | 0.59 | MAOA (0.64) | ALDH1A1LMNAMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5102904-A | N-OXYGENATED ARYLPYRROLE INSECTICIDAL, ACARICIDAL AND NEMATICIDAL AGENTS AND USE THEREAS | AMERICAN CYANAMID COMPANY (US) | 1992-04-07 | — | — | US | claimed |