Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78355 | 0.89 | KDM4E (0.59) | KDM4EDNM1LMNAPOLBPAOX | |
| SCHEMBL9702686 | 0.86 | DNM1 (0.46) | KDM4EDNM1ALDH1A1MEN1HTT | |
| Hydrochloric Acid SCHEMBL10442360 | 0.84 | DNM1 (0.44) | KDM4EDNM1ALDH1A1MEN1HTT | |
| Methacrylic Acid SCHEMBL452014 | 0.83 | KDM4E (0.51) | KDM4EDNM1LMNAPOLBPAOX | |
| SCHEMBL17165990 | 0.83 | KDM4E (0.59) | KDM4EDNM1LMNAPOLBPAOX | |
| SCHEMBL794226 | 0.82 | DNM1 (0.53) | KDM4EDNM1LMNAPOLBPAOX | |
| SCHEMBL1245538 | 0.81 | KDM4E (0.53) | KDM4EDNM1LMNAPOLBPAOX | |
| Acetic Acid SCHEMBL9438497 | 0.80 | KDM4E (0.53) | KDM4EDNM1LMNAPOLBPAOX | |
| Bicarbonate SCHEMBL9017530 | 0.80 | KDM4E (0.53) | KDM4EDNM1LMNAPOLBPAOX | |
| Hydrochloric Acid SCHEMBL793323 | 0.80 | DNM1 (0.52) | KDM4EDNM1PAOXHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5132454-A | Antihypoxic agents | MEIJI SEIKA KAISHA, LTD. (JP) | 1992-07-21 | — | — | US | disclosed |
| US-5066677-A | Antihypoxic agents, treatment of disorders resulting from reduced oxygen supply to brain | MEIJI SEIKA KAISHA, LTD. (JP) | 1991-11-19 | — | — | US | disclosed |
| EP-0387074-A2 | Novel oxamic acid compounds and pharmaceutical composition for use in improvement of damaged cerebral functions of brain | MEIJI SEIKA KAISHA LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |