Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5937187 | 0.84 | APLNR (0.59) | PTGS2NPC1RAB9ASMN1; SMN2APLNR | |
| SCHEMBL5636631 | 0.81 | IDO1 (0.59) | — | |
| SCHEMBL28272270 | 0.81 | CYP1A2 (0.44) | PTGS2CYP1A2CYP3A4SLC6A2RAB9A | |
| SCHEMBL14436807 | 0.78 | PTGS1 (0.58) | PTGS2SLC2A1PTGS1AKR1C3AKR1C2 | |
| SCHEMBL21458247 | 0.77 | MTNR1A (0.41) | PTGS2SLC2A1LMNASMN1; SMN2PDE10A | |
| SCHEMBL21843484 | 0.77 | POLB (0.47) | CYP1A2KDM4ENPC1TP53CYP3A4 | |
| SCHEMBL4529293 | 0.77 | ALDH1A1 (0.44) | PTGS2APLNRCYP19A1CA2KMT2A | |
| SCHEMBL8685698 | 0.76 | CA2 (0.55) | CYP1A2KDM4ELMNACYP3A4MAPT | |
| SCHEMBL4952656 | 0.75 | CA2 (0.58) | PTGS2CYP1A2KDM4ENPC1LMNA | |
| SCHEMBL27763304 | 0.75 | CYP1A2 (0.55) | PTGS2SLC2A1PTGS1AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221677-B1 | P-AMINOPHENOLS, DERIVATIVES THEREOF AND USE FOR MANUFACTURE OF A MEDICAMENT | E.R. Squibb & Sons, Inc. (US) | 1992-09-09 | — | — | EP | disclosed |
| EP-0221677-A2 | p-Aminophenols, derivatives thereof and use for manufacture of a medicament | E.R. Squibb & Sons, Inc. (US) | 1987-05-13 | — | — | EP | disclosed |