Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.72 |
| ▸ | MEN1 | O00255 | 8/20 | 0.72 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256346 | 0.81 | LMNA (0.74) | ATICKMT2AMEN1POLBKDM4E | |
| SCHEMBL30517293 | 0.81 | LMNA (0.78) | ATICKMT2AMEN1POLBKDM4E | |
| SCHEMBL1414326 | 0.81 | LMNA (0.78) | ATICKMT2AMEN1POLBKDM4E | |
| SCHEMBL547543 | 0.79 | KDM4E (1.00) | ATICKMT2AMEN1POLBKDM4E | |
| Sulfaquinoxaline SCHEMBL4435622 | 0.79 | LMNA (1.00) | ATICKMT2AMEN1POLBKDM4E | |
| Sulfaquinoxaline SCHEMBL29391090 | 0.79 | LMNA (1.00) | ATICKMT2AMEN1POLBKDM4E | |
| Sulfaquinoxaline SCHEMBL93789 | 0.79 | LMNA (1.00) | ATICKMT2AMEN1POLBKDM4E | |
| SCHEMBL16091771 | 0.79 | RXFP1 (0.76) | ATICKMT2AMEN1POLBKDM4E | |
| Sulfaquinoxaline SCHEMBL8098708 | 0.78 | ATIC (0.62) | ATICKMT2AMEN1POLBKDM4E | |
| SCHEMBL27896453 | 0.78 | MEN1 (0.78) | ATICKMT2AMEN1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215200-B1 | USE OF SULFANILAMIDO QUINOXALINES IN THE TREATMENT OF NEOPLASTIC DISEASES | MERCK & CO. INC. (US) | 1992-09-09 | — | — | EP | disclosed |