Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATIC | P31939 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 12/20 | 0.54 |
| ▸ | MEN1 | O00255 | 11/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfaquinoxaline SCHEMBL15436955 | 0.84 | KDM4E (0.46) | ATICLMNACYP2C9TDP1KMT2A | |
| SCHEMBL9703960 | 0.78 | ATIC (1.00) | ATICLMNACYP2C9KMT2AMEN1 | |
| Ethopabate SCHEMBL540932 | 0.74 | TDP1 (1.00) | LMNATDP1KMT2AMEN1MAPT | |
| Ethopabate SCHEMBL29625103 | 0.74 | TDP1 (1.00) | LMNATDP1KMT2AMEN1MAPT | |
| Sulfaquinoxaline SCHEMBL29391090 | 0.74 | LMNA (1.00) | ATICLMNACYP2C9KMT2AMEN1 | |
| Sulfaquinoxaline SCHEMBL4435622 | 0.74 | LMNA (1.00) | ATICLMNACYP2C9KMT2AMEN1 | |
| Sulfaquinoxaline SCHEMBL93789 | 0.74 | LMNA (1.00) | ATICLMNACYP2C9KMT2AMEN1 | |
| Sulfaquinoxaline SCHEMBL301314 | 0.73 | LMNA (0.97) | ATICLMNACYP2C9KMT2AMEN1 | |
| Sulfaquinoxaline SCHEMBL27961007 | 0.73 | LMNA (0.97) | ATICLMNACYP2C9KMT2AMEN1 | |
| Ethopabate SCHEMBL28629644 | 0.73 | TDP1 (0.97) | LMNATDP1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6034116-A | VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 2000-03-07 | — | — | US | disclosed |