Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9703948 | 0.81 | ATM (0.37) | HIF1AATMNPC1GAARAB9A | |
| SCHEMBL9704210 | 0.76 | PGK1 (0.36) | HIF1AATMNPC1GAARAB9A | |
| SCHEMBL9703450 | 0.74 | GAA (0.43) | HIF1AATMGAAALDH1A1 | |
| SCHEMBL9704991 | 0.70 | GRIN2D (0.45) | — | |
| SCHEMBL9703955 | 0.61 | HRH4 (0.43) | GAARAB9AALDH1A1 | |
| SCHEMBL9703518 | 0.60 | GAA (0.47) | ATMNPC1GAARAB9A | |
| SCHEMBL9703688 | 0.56 | NPC1 (0.45) | ATMNPC1RAB9AALDH1A1 | |
| SCHEMBL11278799 | 0.56 | MMP1 (0.40) | ALDH1A1 | |
| SCHEMBL4007574 | 0.55 | CDK1 (0.45) | ATMGAA | |
| SCHEMBL31186096 | 0.55 | SMN1; SMN2 (0.42) | HIF1ANPC1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |