⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10751495 | 0.77 | NOS1 (0.32) | — | |
| SCHEMBL128494 | 0.75 | — | — | |
| SCHEMBL440250 | 0.74 | — | — | |
| SCHEMBL2853189 | 0.74 | — | — | |
| SCHEMBL278457 | 0.74 | — | — | |
| SCHEMBL20503389 | 0.73 | PDE4B (0.31) | — | |
| SCHEMBL22798031 | 0.71 | GPR119 (0.33) | — | |
| SCHEMBL11034901 | 0.69 | ELANE (0.31) | — | |
| SCHEMBL6606610 | 0.69 | — | — | |
| SCHEMBL601253 | 0.69 | FDPS (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368040-A | Diaryl monocyclic β -lactam compounds and methods of use thereof for treating bacterial infections | 默沙东公司 | 2018-08-03 | — | — | CN | disclosed |
| EP-0192210-B1 | CEPHEM COMPOUNDS AND PROCESSES FOR PREPARATION THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | disclosed |
| US-4973699-A | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| US-4861769-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-08-29 | — | — | US | disclosed |
| EP-0192210-A2 | Cephem compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-08-27 | — | — | EP | disclosed |