Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705305 | 0.80 | GRIN2B (0.34) | DPP4 | |
| SCHEMBL9052081 | 0.70 | — | — | |
| SCHEMBL18342156 | 0.69 | SMN1; SMN2 (0.36) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL28960605 | 0.68 | ALDH1A1 (0.47) | MAPTMAPK1NPSR1L3MBTL1LMNA | |
| Hydrochloric Acid SCHEMBL27552872 | 0.67 | ALDH1A1 (0.45) | MAPTMAPK1NPSR1L3MBTL1LMNA | |
| SCHEMBL5140398 | 0.65 | GAA (0.37) | MAPTMAPK1NPSR1L3MBTL1LMNA | |
| SCHEMBL14463170 | 0.65 | ALDH1A1 (0.47) | MAPTMAPK1NPSR1L3MBTL1LMNA | |
| SCHEMBL6209753 | 0.65 | SMN1; SMN2 (0.43) | MAPTMAPK1NPSR1L3MBTL1LMNA | |
| SCHEMBL8239452 | 0.65 | OPRM1 (0.36) | LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6209743 | 0.65 | SMN1; SMN2 (0.43) | MAPTMAPK1NPSR1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0209643-B1 | PEPTIDE COMPOSITION USEFUL FOR THE MALARIA VACCINE MANUFACTURE AS WELL AS FOR THE PREPARATION OF DIAGNOSTIC KITS FOR THE DETECTION OF MALARIAL DISEASES | ENIRICERCHE S.p.A. (IT) | 1992-07-08 | — | — | EP | disclosed |
| US-4956449-A | Forming polypeptides from tetrapeptides condensed and separated by chromatography | ENIRICERCHE, S.P.A. (IT) | 1990-09-11 | — | — | US | disclosed |
| EP-0209643-A2 | Peptide composition useful for the malaria vaccine manufacture as well as for the preparation of diagnostic kits for the detection of malarial diseases | ENIRICERCHE S.p.A. (IT) | 1987-01-28 | — | — | EP | disclosed |