Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | AANAT | Q16613 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559245 | 0.84 | MEN1 (0.68) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL27174179 | 0.82 | HTR2A (0.66) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL6702312 | 0.81 | MTNR1A (0.67) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL6425177 | 0.81 | MEN1 (0.61) | MEN1KMT2ALMNACYP1A2PKM | |
| Nb-Acetyltryptamine SCHEMBL468850 | 0.79 | MEN1 (1.00) | MEN1KMT2ALMNACYP1A2PKM | |
| Methyl Carbamate SCHEMBL6828080 | 0.79 | MEN1 (0.61) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL678380 | 0.79 | HTR2A (0.69) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL28242499 | 0.79 | HTR2A (0.64) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL6424923 | 0.79 | MEN1 (0.61) | MEN1KMT2ALMNACYP1A2PKM | |
| SCHEMBL6425980 | 0.79 | MEN1 (0.61) | MEN1KMT2ALMNACYP1A2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250064701-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | UNIVERSIDAD DE GRANADA (ES) | 2025-02-27 | — | — | US | disclosed |
| US-20230414470-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | UNIVERSIDAD DE GRANADA (ES) | 2023-12-28 | — | — | US | disclosed |
| US-20230031519-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | UNIVERSIDAD DE GRANADA (ES) | 2023-02-02 | — | — | US | disclosed |
| US-11234964-B2 | Use of melatonin for the treatment of tumors | UNIVERSIDAD DE GRANADA (ES) | 2022-02-01 | — | — | US | disclosed |
| US-20210106562-A1 | USE OF MELATONIN FOR THE TREATMENT OF TUMOURS | UNIVERSIDAD DE GRANADA (ES) | 2021-04-15 | — | — | US | disclosed |
| EP-3603635-A2 | USE OF MELATONIN FOR THE TREATMENT OF TUMOURS | Universidad de Granada (ES) | 2020-02-05 | — | — | EP | disclosed |
| EP-2926800-B1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | UNIV GRANADA (ES) | 2019-05-29 | — | — | EP | disclosed |
| US-20180311133-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | UNIVERSIDAD DE GRANADA (ES) | 2018-11-01 | — | — | US | disclosed |
| US-10092544-B2 | Composition comprising melatonin or its derivatives with coenzyme Q10 and use thereof against ageing of the skin | UNIVERSIDAD DE GRANADA (ES) | 2018-10-09 | — | — | US | disclosed |
| EP-2702992-B1 | USE OF MELATONIN FOR TREATING AND/OR PREVENTING MUCOSITIS | UNIV GRANADA (ES) | 2017-09-27 | — | — | EP | disclosed |
| WO-2014083227-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | UNIVERSIDAD DE GRANADA (ES) | 2014-06-05 | — | — | WO | disclosed |
| EP-2702992-A1 | USE OF MELATONIN FOR TREATING AND/OR PREVENTING MUCOSITIS | Universidad de Granada (ES) | 2014-03-05 | — | — | EP | disclosed |
| WO-2013178587-A1 | USE OF N-ACETYL-5-METHOXYTRYPTAMINE OR ANALOGUES THEREOF, FOR PROMOTING THE MECHANISM OF IMPLANTATION OF THE EMBRYO AND RELATED COMPOSITIONS AND CULTURE MEDIA | MAXIA NICOLETTA (IT) | 2013-12-05 | — | — | WO | disclosed |
| WO-2013057354-A1 | USE OF MELATONIN FOR TREATING AND/OR PREVENTING MUCOSITIS | UNIVERSIDAD DE GRANADA (ES) | 2013-04-25 | — | — | WO | disclosed |
| EP-0214254-B1 | MELATONIN COMPOSITIONS AND USES THEREOF | CELLENA (CELL ENGINEERING) A.G. (CH) | 1992-06-17 | — | — | EP | disclosed |
| US-4746674-A | Melatonin compositions and uses thereof | CELLENA (CELL ENGINEERING) AG (CH) | 1988-05-24 | — | — | US | disclosed |
| EP-0229131-A1 | USE OF MELATONIN OR RELATED COMPOUNDS FOR THE TREATMENT OF PSORIASIS | CELLENA (CELL ENGENEERING) A.G. (CH) | 1987-07-22 | — | — | EP | disclosed |
| EP-0214254-A1 | MELATONIN COMPOSITIONS AND USES THEREOF. | CELL ENG AG (CH) | 1987-03-18 | — | — | EP | disclosed |
| WO-1987000432-A2 | USE OF MELATONIN OR RELATED COMPOUNDS FOR THE TREATMENT OF PSORIASIS | CELLENA (CELL ENGINEERING) A.G. (CH) | 1987-01-29 | — | — | WO | disclosed |
| WO-1986005093-A2 | MELATONIN COMPOSITIONS AND USES THEREOF | CELLENA (CELL ENGINEERING) A.G. (CH) | 1986-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230414470-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | NDUFA10, NDUFB10, TIMM10 | MEN1 585/4885KMT2A 2271/4885LMNA 682/4885 |
| US-20250064701-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | NDUFA10, NDUFB10, TIMM10 | MEN1 585/4885KMT2A 2271/4885LMNA 682/4885 |
| US-10092544-B2 | Composition comprising melatonin or its derivatives with coenzyme Q10 and use thereof against ageing of the skin | NDUFA10, NDUFB10, TIMM10 | MEN1 585/4885KMT2A 2271/4885LMNA 682/4885 |
| US-11234964-B2 | Use of melatonin for the treatment of tumors | MTNR1A, MTNR1B, MFN2 | MEN1 211/4885KMT2A 1024/4885LMNA 1138/4885 |
| US-20210106562-A1 | USE OF MELATONIN FOR THE TREATMENT OF TUMOURS | MTNR1A, MTNR1B, MFN2 | MEN1 190/4885KMT2A 1027/4885LMNA 1205/4885 |
| US-20180311133-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | NDUFA10, NDUFB10, TIMM10 | MEN1 585/4885KMT2A 2271/4885LMNA 682/4885 |
| US-20230031519-A1 | COMPOSITION COMPRISING MELATONIN OR ITS DERIVATIVES WITH COENZYME Q10 AND USE THEREOF AGAINST AGEING OF THE SKIN | NDUFA10, NDUFB10, TIMM10 | MEN1 585/4885KMT2A 2271/4885LMNA 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.