Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186704 | 1.00 | TDP1 (0.39) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9032259 | 0.90 | TDP1 (0.38) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL7192028 | 0.84 | TDP1 (0.37) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9871979 | 0.79 | TDP1 (0.41) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9032262 | 0.76 | TDP1 (0.36) | TDP1ATMALDH1A1MAPTHPGD | |
| SCHEMBL9670137 | 0.73 | ALDH1A1 (0.39) | TDP1ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL2944429 | 0.73 | RAB9A (0.35) | TDP1ATMRAB9A | |
| SCHEMBL10493918 | 0.73 | ALDH1A1 (0.37) | ALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL9168542 | 0.73 | RAB9A (0.35) | TDP1ATMRAB9A | |
| SCHEMBL10759407 | 0.73 | RAB9A (0.35) | TDP1ATMALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508234-A2 | Beta-lactames | F. HOFFMANN-LA ROCHE AG (CH) | 1992-10-14 | — | — | EP | disclosed |