Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | YAP1 | P46937 | 3/20 | 0.33 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9705697 | 0.80 | GRIN2B (0.34) | CTSLYAP1KLK7HTR2CSLC6A4 | |
| SCHEMBL9556587 | 0.77 | CTSL (0.39) | CTSLKLK7HTR2CMEN1KMT2A | |
| SCHEMBL7542372 | 0.74 | IL6ST (0.40) | CTSLKLK7REN | |
| SCHEMBL7542380 | 0.74 | IL6ST (0.40) | CTSLKLK7REN | |
| SCHEMBL7542377 | 0.74 | IL6ST (0.40) | CTSLKLK7REN | |
| SCHEMBL7395740 | 0.73 | REN (0.39) | GPR119REN | |
| SCHEMBL10595540 | 0.73 | REN (0.39) | GPR119REN | |
| SCHEMBL10595542 | 0.73 | REN (0.39) | GPR119REN | |
| SCHEMBL9845923 | 0.73 | GPR119 (0.37) | CTSLMEN1KMT2ACTSSGPR119 | |
| SCHEMBL7344330 | 0.73 | SPHK1 (0.34) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487980-A1 | Aminodiols-derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-06-03 | — | — | EP | disclosed |