Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028324 | 0.85 | L3MBTL1 (0.51) | RECQLHTTMAPTALDH1A1LMNA | |
| SCHEMBL9704241 | 0.85 | MAPT (0.57) | RECQLMAPTALDH1A1LMNAGAA | |
| SCHEMBL8190013 | 0.83 | LMNA (0.64) | RECQLHTTMAPTALDH1A1LMNA | |
| SCHEMBL11445790 | 0.81 | TSHR (0.52) | RECQLHTTMAPTALDH1A1LMNA | |
| SCHEMBL11435301 | 0.81 | ALDH1A1 (0.54) | RECQLHTTMAPTALDH1A1LMNA | |
| SCHEMBL31554429 | 0.80 | MEN1 (0.52) | MAPTALDH1A1LMNAGAAKMT2A | |
| SCHEMBL11257676 | 0.80 | RECQL (0.51) | RECQLHTTMAPTALDH1A1LMNA | |
| SCHEMBL11446316 | 0.80 | L3MBTL1 (0.51) | RECQLHTTMAPTALDH1A1LMNA | |
| SCHEMBL3706025 | 0.80 | L3MBTL1 (0.69) | RECQLHTTMAPTALDH1A1LMNA | |
| SCHEMBL30623198 | 0.80 | PKM (0.67) | RECQLHTTMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |