Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.33 |
| ▸ | KDM4A | O75164 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL20474536 | 0.83 | TSHR (0.32) | ENPEPTSHRLMNA | |
| SCHEMBL2940408 | 0.83 | CHRM1 (0.35) | ENPEPTSHRLMNATDP1CHRM1 | |
| SCHEMBL30927189 | 0.83 | PMP22 (0.36) | ENPEPTSHRLMNAALDH1A1CYP1A2 | |
| SCHEMBL4128716 | 0.81 | ENPEP (0.37) | ENPEPTSHRLMNAALDH1A1TDP1 | |
| SCHEMBL5856024 | 0.79 | TBXAS1 (0.36) | ENPEPTSHRLMNAALDH1A1TDP1 | |
| SCHEMBL11059588 | 0.79 | TET2 (0.33) | TET2TET3GRIK1GRIK2GRM1 | |
| SCHEMBL28123 | 0.78 | ENPEP (0.55) | ENPEPTSHRLMNAALDH1A1TDP1 | |
| SCHEMBL18542801 | 0.78 | TSHR (0.30) | TSHR | |
| SCHEMBL28314785 | 0.77 | LTA4H (0.34) | TET2KDM4AKDM4CKDM2AFOLH1 | |
| SCHEMBL6474908 | 0.77 | TBXAS1 (0.39) | ENPEPTSHRLMNAALDH1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11781128-B2 | Methods for producing hybrid polyketide synthase genes and polyketides | ISOMERASE THERAPEUTICS LIMITED (GB) | 2023-10-10 | — | — | US | disclosed |
| EP-3960857-A1 | NOVEL METHODS | Isomerase Therapeutics Limited (GB) | 2022-03-02 | — | — | EP | disclosed |
| EP-3491132-B1 | METHODS AND CONSTRUCTS FOR PRODUCING HYBRID POLYKETIDES (PKS) OF A TYPE 1 MODULAR PKS OR HYBRID MODULAR NON RIBOSOMAL PEPTIDES (NRPS) | ISOMERASE THERAPEUTICS LTD (GB) | 2021-09-08 | — | — | EP | disclosed |
| EP-3491132-A1 | NOVEL METHODS | Isomerase Therapeutics Limited (GB) | 2019-06-05 | — | — | EP | disclosed |
| WO-2018020272-A1 | NOVEL METHODS | ISOMERASE THERAPEUTICS LIMITED (GB) | 2018-02-01 | — | — | WO | disclosed |
| US-8815892-B2 | P2X7R antagonists and their use | AFFECTIS PHARMACEUTICALS AG (DE) | 2014-08-26 | — | — | US | disclosed |
| US-20130197046-A1 | NOVEL P2X7R ANTAGONISTS AND THEIR USE | AFFECTIS PHARMACEUTICALS AG (DE) | 2013-08-01 | — | — | US | disclosed |
| WO-1992011245-A1 | 2-ACYLAMIDO DERIVATIVES OF 3,4-DIHYDRO-3-OXO-QUINOXALINE HAVING PHARMACEUTICAL ACTIVITY | WARNER-LAMBERT COMPANY (US) | 1992-07-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197046-A1 | NOVEL P2X7R ANTAGONISTS AND THEIR USE | P2RX3, P2RX7, P2RX2 | ENPEP 3150/4885TSHR 872/4885LMNA 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.