Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | POLA1 | P09884 | 2/20 | 0.53 |
| ▸ | POLD1 | P28340 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.45 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 2/20 | 0.43 |
| ▸ | TK1 | P04183 | 3/20 | 0.42 |
| ▸ | P2RY4 | P51582 | 2/20 | 0.41 |
| ▸ | POLG | P54098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27389186 | 0.98 | POLB (0.50) | POLBPOLA1POLD1LMNAALOX12 | |
| SCHEMBL9706045 | 0.90 | LMNA (0.53) | LMNAALOX12ADRA1ASMN1; SMN2TYMS | |
| SCHEMBL7906708 | 0.87 | POLB (0.55) | POLBPOLA1POLD1LMNASMN1; SMN2 | |
| SCHEMBL22110712 | 0.87 | POLB (0.55) | POLBPOLA1POLD1LMNASMN1; SMN2 | |
| SCHEMBL7906710 | 0.87 | POLB (0.55) | POLBPOLA1POLD1LMNASMN1; SMN2 | |
| SCHEMBL265387 | 0.86 | POLB (0.68) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL3031874 | 0.86 | POLB (0.68) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL9706042 | 0.86 | LMNA (0.49) | POLBPOLA1POLD1LMNAALOX12 | |
| SCHEMBL30586988 | 0.86 | POLB (0.68) | POLBPOLA1POLD1P2RY2P2RY6 | |
| SCHEMBL77582 | 0.86 | POLB (0.68) | POLBPOLA1POLD1P2RY2P2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720603-B | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117720603-A | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-117720603-B | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117720603-B | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117720603-B | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117720603-A | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117720603-A | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-117720603-A | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2015089511-A2 | MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2015-06-18 | — | — | WO | disclosed |
| EP-0507188-A1 | Substituted 2',3'-dideoxy-5-trifluoromethyluridines, method of their preparation and their use in medicaments | BAYER AG (DE) | 1992-10-07 | — | — | EP | disclosed |