Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.32 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23174645 | 0.97 | CES2 (0.37) | CES2TSHRALDH1A1IDO1NOS3 | |
| SCHEMBL6537833 | 0.97 | CES2 (0.37) | CES2TSHRALDH1A1IDO1NOS3 | |
| SCHEMBL697742 | 0.83 | ALDH1A1 (0.35) | CES2TSHRALDH1A1CYP3A4HPGD | |
| SCHEMBL16390881 | 0.83 | CES2 (0.37) | CES2LMNAGPR35 | |
| SCHEMBL697546 | 0.83 | CES2 (0.32) | CES2 | |
| SCHEMBL1841922 | 0.81 | — | — | |
| SCHEMBL3337947 | 0.78 | NOTUM (0.32) | IDO1GPR35 | |
| SCHEMBL16986315 | 0.78 | — | — | |
| SCHEMBL1842608 | 0.76 | — | — | |
| SCHEMBL6223113 | 0.75 | ALDH1A1 (0.46) | TSHRALDH1A1CYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 728 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11261290-B2 | Method for the polymerization of cycloolefins by means of ring-opening metathesis | DEMETA (FR) | 2022-03-01 | — | — | US | claimed |
| US-20200339741-A1 | METHOD FOR THE POLYMERISATION OF CYCLOOLEFINS BY MEANS OF RING-OPENING METATHESIS | VIPO FRANCE SAS (FR) | 2020-10-29 | — | — | US | claimed |
| EP-3728391-A1 | METHOD FOR THE POLYMERISATION OF CYCLOOLEFINS BY MEANS OF RING-OPENING METATHESIS | Demeta (FR) | 2020-10-28 | — | — | EP | claimed |
| WO-2020099750-A1 | METHOD FOR THE METATHESIS OF OLEFINS USING A CATALYST IN THE PRESENCE OF AN ACTIVATOR AND A RETARDING AGENT | DEMETA (FR) | 2020-05-22 | — | — | WO | claimed |
| EP-3404017-B1 | FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF | NISSAN CHEMICAL IND LTD (JP) | 2020-05-13 | — | — | EP | claimed |
| US-10590287-B2 | Charge-transporting varnish and organic electroluminescent element | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2020-03-17 | — | — | US | claimed |
| EP-3309851-B1 | CHARGE-TRANSPORTING VARNISH AND ORGANIC ELECTROLUMINESCENT ELEMENT | NISSAN CHEMICAL CORP (JP) | 2020-01-01 | — | — | EP | claimed |
| EP-2931709-B1 | PROCESS FOR PREPARING ASYMMETRICAL IMIDAZOLIUM SALTS | ECOLE NAT SUPERIEURE DE CHIMIE DE RENNES (FR) | 2019-10-02 | — | — | EP | claimed |
| US-10336686-B2 | Fluorine atom-containing compound and use thereof | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-07-02 | — | — | US | claimed |
| US-20190031600-A1 | FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2019-01-31 | — | — | US | claimed |
| WO-1999067221-A1 | COMPOUNDS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | claimed |
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | claimed |
| US-5932393-A | Borate photoinitiators from monoboranes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-08-03 | — | — | US | claimed |
| EP-0919571-A1 | Catalyst composition comprising a reduced transition metal complex and a cocatalyst | DSM N.V. (NL) | 1999-06-02 | — | — | EP | claimed |
| WO-1999006414-A1 | COMPOUNDS CONTAINING BORON AND ALUMINIUM | TARGOR GMBH (DE) | 1999-02-11 | — | — | WO | claimed |
| WO-1998038177-A1 | HETEROCYCLIC COMPOUNDS AND THEIR USE FOR INHIBITING β-AMYLOID PEPTIDE | ELAN PHARMACEUTICALS, INC. (US) | 1998-09-03 | — | — | WO | claimed |
| EP-0627926-B1 | PEPTIDYL DERIVATIVES AS INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME | MERCK & CO INC (US) | 1998-08-05 | — | — | EP | claimed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | claimed |
| EP-0824113-A1 | Supported catalyst, process for its preparation and its use in olefin polymerization | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-02-18 | — | — | EP | claimed |
| WO-1997010220-A1 | URACIL DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-20 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336686-B2 | Fluorine atom-containing compound and use thereof | ARF1, ARF5, ARFGAP1 | CES2 2869/4885TSHR 668/4885ALDH1A1 982/4885 |
| US-10590287-B2 | Charge-transporting varnish and organic electroluminescent element | SLCO4C1, SLCO2A1, SLC26A3 | CES2 398/4885TSHR 1837/4885ALDH1A1 378/4885 |
| US-20190031600-A1 | FLUORINE ATOM-CONTAINING COMPOUND AND USE THEREOF | ARF1, ARF5, ARFGAP1 | CES2 2869/4885TSHR 668/4885ALDH1A1 982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.