Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.42 |
| ▸ | EEF2K | O00418 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.38 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.38 |
| ▸ | XIAP | P98170 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL932791 | 0.81 | ALOX5 (0.51) | ALDH1A1CYP2C9CYP2C19ALOX5MPEG1 | |
| Butylated Hydroxytoluene SCHEMBL28288111 | 0.77 | CA2 (0.75) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| SCHEMBL5554116 | 0.74 | ALOX5 (0.62) | ALDH1A1CYP2C9CYP2C19ALOX5MPEG1 | |
| SCHEMBL27904845 | 0.74 | ALOX5 (0.62) | ALDH1A1CYP2C9CYP2C19ALOX5MPEG1 | |
| SCHEMBL9114680 | 0.73 | HSPA5 (0.66) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL17263856 | 0.70 | CA2 (0.75) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL6655653 | 0.70 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL28414857 | 0.70 | ALDH1A1 (0.62) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL994118 | 0.70 | ALDH1A1 (0.82) | SMN1; SMN2ALDH1A1CA2POLBTYR | |
| Butylated Hydroxytoluene SCHEMBL453824 | 0.70 | SMN1; SMN2 (1.00) | SMN1; SMN2ALDH1A1CA2POLBTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202512-B1 | NICOTINE DISPENSER WITH POLYMERIC RESERVOIR OF NICOTINE | Kabi Pharmacia AB (SE) | 1992-06-17 | — | — | EP | claimed |
| US-4800903-A | POLYOLEFIN POROSITY PLUG IN TUBE-REVERSIBLE ABSORBER | PHARMACIA, INC. | 1989-01-31 | — | — | US | claimed |
| EP-0202512-A2 | Nicotine dispenser with polymeric reservoir of nicotine | Kabi Pharmacia AB (SE) | 1986-11-26 | — | — | EP | claimed |