Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | GNRHR | P30968 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706685 | 0.83 | HPGD (0.35) | GNRHRKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9706663 | 0.82 | NOTUM (0.40) | NOTUMGNRHRKDM4EMYCNR4A1 | |
| SCHEMBL9706638 | 0.82 | NOTUM (0.34) | NOTUMGNRHRMYCNR4A1CTSB | |
| SCHEMBL9706705 | 0.80 | NOTUM (0.37) | NOTUMGNRHRKDM4EMYCNR4A1 | |
| SCHEMBL9706646 | 0.76 | NOTUM (0.37) | NOTUMMYCNR4A1CTSBTDP1 | |
| SCHEMBL10575583 | 0.76 | PPOX (0.45) | GNRHRTDP1HTTMEN1KMT2A | |
| SCHEMBL9706673 | 0.75 | HPGD (0.40) | KDM4ETDP1EPHX2MEN1ALDH1A1 | |
| SCHEMBL9706536 | 0.75 | HPGD (0.38) | KDM4ETDP1HTTEPHX2MEN1 | |
| SCHEMBL9706539 | 0.75 | SMN1; SMN2 (0.45) | NOTUMMYCNR4A1CTSBTDP1 | |
| SCHEMBL9706655 | 0.75 | TSHR (0.34) | NOTUMKDM4EMYCNR4A1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0195346-B1 | 3-ARYL URACILES AND THEIR USE AS HERBICIDES | CIBA-GEIGY AG (CH) | 1992-06-24 | — | — | EP | claimed |