SCHEMBL9765289

SCHEMBL9765289

CCC(Cc1ccc(O)cc1)NS(=O)(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 4/20 0.62
PGR P06401 4/20 0.62
NR3C2 P08235 4/20 0.62
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
PIN1 Q13526 1/20 0.53
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
PRKCG P05129 4/20 0.48
PRKCB P05771 4/20 0.48
PRKCA P17252 4/20 0.48
PRKCE Q02156 4/20 0.48
PRKCD Q05655 4/20 0.48
PRKACA P17612 1/20 0.48
PRKACG P22612 1/20 0.48
PRKACB P22694 1/20 0.48
MMP2 P08253 4/20 0.48
MMP9 P14780 3/20 0.48
ADAMTS4 O75173 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9707094 0.82 ALDH1A1 (0.57) KMT2AMEN1L3MBTL1PIN1MMP2
SCHEMBL9707087 0.82 ALDH1A1 (0.57) KMT2AMEN1L3MBTL1PIN1MMP2
SCHEMBL9765320 0.82 ALDH1A1 (0.57) KMT2AMEN1L3MBTL1PIN1MMP2
SCHEMBL8912956 0.81 L3MBTL1 (0.78) KMT2AMEN1L3MBTL1MMP2MMP9
SCHEMBL9765314 0.81 TBXA2R (0.58) PIN1CA2CA7MMP2MMP9
SCHEMBL9512132 0.81 MMP2 (0.60) KMT2AMEN1L3MBTL1PIN1CA2
SCHEMBL6368625 0.79 SMN1; SMN2 (0.54) L3MBTL1PIN1CA2CA7MMP2
SCHEMBL7984123 0.77 POLB (0.60) KMT2AMEN1L3MBTL1CA2CA7
SCHEMBL9765262 0.77 ALDH1A1 (0.53) KMT2AMEN1L3MBTL1PRKCGPRKCB
SCHEMBL5261326 0.75 SMN1; SMN2 (0.68) PIN1CA2CA7MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0255728-B1 PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE TANABE SEIYAKU CO., LTD. (JP) 1991-11-27 EP disclosed
US-4866196-A ANTICOAGULANTS TANABE SEIYAKU CO., LTD. (JP) 1989-09-12 US disclosed
EP-0255728-A2 Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use TANABE SEIYAKU CO., LTD. (JP) 1988-02-10 EP disclosed