Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | NSD2 | O96028 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL9055346 | 0.91 | MAPT (0.58) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| Sulfuric Acid SCHEMBL475959 | 0.91 | MAPT (0.58) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| Sulfuric Acid SCHEMBL498037 | 0.89 | RAPGEF4 (0.56) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| Diphenylamine SCHEMBL1008716 | 0.87 | HSD17B10 (0.67) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| Diphenylamine SCHEMBL28015233 | 0.87 | HSD17B10 (0.67) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| Diphenylamine SCHEMBL1008717 | 0.87 | HSD17B10 (0.67) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| SCHEMBL6405773 | 0.87 | ALDH1A1 (1.00) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| SCHEMBL22282997 | 0.87 | ALDH1A1 (1.00) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| SCHEMBL28848194 | 0.87 | ALDH1A1 (1.00) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 | |
| SCHEMBL15371 | 0.87 | ALDH1A1 (1.00) | MAPTALDH1A1L3MBTL1ALOX12CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | AVOCA LLC | 2011-01-27 | — | — | US | claimed |
| EP-1429715-B1 | HAIR COLOURING COMPOSITIONS | BOOTS CO PLC (GB) | 2010-11-24 | — | — | EP | claimed |
| US-7172632-B2 | Hair coloring compositions | THE BOOTS COMPANY, PLC (GB) | 2007-02-06 | — | — | US | claimed |
| US-20050039269-A1 | Hair colouring compositions | BOOTS COMPANY PLC, THE (GB) | 2005-02-24 | — | — | US | claimed |
| EP-1429715-A2 | HAIR COLOURING COMPOSITIONS | The Boots Company PLC (GB) | 2004-06-23 | — | — | EP | claimed |
| WO-2003015734-A2 | HAIR COLOURING COMPOSITIONS | THE BOOTS COMPANY PLC (GB) | 2003-02-27 | — | — | WO | claimed |
| US-4171952-A | 1,5-DIHYDROXYNAPHTHALENE, 4,4'-DIAMINODIPHENYLAMINE, P-AMINODIPHENYLAMINE, MODIFIER, COUPLER, BASE | SYNTEX (U.S.A.) INC. (US) | 1979-10-23 | — | — | US | claimed |
| US-4169703-A | A MIXTURE OF 1-NAPHTHOL, P-AMINOPHENOL, A MODIFIER, AND A COUPLER | SYNTEX (U.S.A.) INC. (US) | 1979-10-02 | — | — | US | claimed |
| US-4169704-A | A MIXTURE OF M- AND P-AMINOPHENOL, P-METHYLAMINOPHENOL OR ACID ADDITION SALT, MODIFIER, AND COUPLER | SYNTEX (U.S.A.) INC. (US) | 1979-10-02 | — | — | US | claimed |
| US-4104021-A | OXIDATION COLOR DYES | COMBE INCORPORATED (US) | 1978-08-01 | — | — | US | claimed |
| US-10064471-B2 | Air oxidation hair dye application system and method for coloring hair using the same | COMBE INCORPORATED (US) | 2018-09-04 | — | — | US | disclosed |
| CN-101990406-B | Air oxidation hair dye application system and method for dyeing hair using same | COMBE INTERNAT LTD | 2014-11-05 | — | — | CN | disclosed |
| EP-2211657-B1 | AIR OXIDATION HAIR DYE APPLICATION SYSTEM AND METHOD FOR COLORING HAIR USING THE SAME | COMBE INTERNAT LTD (US) | 2014-04-30 | — | — | EP | disclosed |
| US-8673272-B2 | Ultraviolet-absorbing compounds | ISP INVESTMENTS INC. (US) | 2014-03-18 | — | — | US | disclosed |
| CN-101990406-A | Air oxidation hair dye application system and method for dyeing hair using same | COMBE INTERNAT LTD | 2011-03-23 | — | — | CN | disclosed |
| WO-2001007009-A1 | LYSINE OXIDASE LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| WO-2001006829-A2 | LINKAGE OF AGENTS TO TISSUE | PERICOR SCIENCE, INC. (US) | 2001-02-01 | — | — | WO | disclosed |
| US-4169703-A | A MIXTURE OF 1-NAPHTHOL, P-AMINOPHENOL, A MODIFIER, AND A COUPLER | SYNTEX (U.S.A.) INC. (US) | 1979-10-02 | — | — | US | disclosed |
| US-4169704-A | A MIXTURE OF M- AND P-AMINOPHENOL, P-METHYLAMINOPHENOL OR ACID ADDITION SALT, MODIFIER, AND COUPLER | SYNTEX (U.S.A.) INC. (US) | 1979-10-02 | — | — | US | disclosed |
| US-4104021-A | OXIDATION COLOR DYES | COMBE INCORPORATED (US) | 1978-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110020251-A1 | Ultraviolet-Absorbing Compounds | UFM1, UHRF1, CUTA | SLC6A2 4166/4885MAPT 322/4885ALDH1A1 152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.