Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TPH2 | Q8IWU9 | 19/20 | 0.47 |
| ▸ | TPH1 | P17752 | 18/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707703 | 0.94 | TPH1 (0.49) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9708297 | 0.91 | MEN1 (0.54) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9708617 | 0.91 | MEN1 (0.42) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9708838 | 0.91 | MEN1 (0.44) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9708307 | 0.91 | MEN1 (0.47) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9708124 | 0.90 | MEN1 (0.55) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9708631 | 0.90 | ALDH1A1 (0.47) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9707658 | 0.90 | KMT2A (0.41) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9708313 | 0.89 | MEN1 (0.44) | MEN1KMT2ATPH2TPH1 | |
| SCHEMBL9708221 | 0.89 | MEN1 (0.41) | MEN1KMT2ATPH2TPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |