Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.46 |
| ▸ | USP1 | O94782 | 6/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.39 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9707871 | 0.95 | ADORA3 (0.42) | DCTPP1USP1KMT2AMEN1 | |
| SCHEMBL9708054 | 0.94 | USP1 (0.42) | DCTPP1USP1THRBKMT2AMEN1 | |
| SCHEMBL9707692 | 0.92 | ADORA3 (0.40) | DCTPP1USP1KMT2AMEN1 | |
| SCHEMBL9707777 | 0.92 | ADORA3 (0.42) | USP1 | |
| SCHEMBL9707508 | 0.92 | ADORA3 (0.42) | USP1 | |
| SCHEMBL9707745 | 0.91 | ADORA2A (0.39) | DCTPP1USP1KMT2AMEN1 | |
| SCHEMBL9708648 | 0.91 | ADORA1 (0.42) | USP1RAB9ADPP4 | |
| SCHEMBL9708047 | 0.91 | USP1 (0.39) | DCTPP1USP1KMT2AMEN1 | |
| SCHEMBL9708021 | 0.91 | ADORA3 (0.42) | DCTPP1USP1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9707419 | 0.91 | ADORA3 (0.42) | DCTPP1USP1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992007852-A1 | BIPHENYLALKYL XANTHINE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1992-05-14 | — | — | WO | disclosed |